A Quarterly Publication of City of Hope | Volume 18 Number 3 | Summer 2007

CHAPTERS

You can help spread the word about City of Hope

.You can help spread the word about City of Hope

Increasing coverage in newspapers, radio, television and the Web testify to City of Hope’s reputation nationwide as a leading cancer center and biomedical research institute.

In 2007, media coverage of City of Hope reached a total of 240 million readers, viewers and listeners — 8 million more than the previous year. The institution’s profile also grew through promotional public service announcements broadcast over Clear Channel radio stations across the United States featuring well-known entertainers such as Sheryl Crow and Kiefer Sutherland.

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Playful nature belied true nature of a committed philanthropist

Playful nature belied true nature of a committed philanthropist

Greta Flaschner was exuberant, playful and had a zest for life. She was lighthearted with those closest to her, but was quite serious about her philanthropy, as evidenced by a $2.9 million real estate bequest she left to City of Hope.

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EVENTS AND ANNOUNCEMENTS

New center deemed a lifeline for patients needing blood products

New center deemed a lifeline for patients needing blood products

On any given day, the lives of dozens of men, women and children in treatment at City of Hope depend on delicate cells — cells gathered from their own blood or that of others. Soon, many more patients will be able to receive these crucial cells, thanks to a generous business leader.

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Walk for Hope takes crucial fight against breast cancer to the nation’s streets

Walk for Hope takes crucial fight against breast cancer to the nation’s streets

More than 26,000 participants hit the streets of nine American cities last year in a team effort to eradicate the leading cancer among women through City of Hope’s Walk for Hope to Cure Breast Cancer.

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FIRST PERSON: PATIENT PROFILE

FIRST PERSON: PATIENT PROFILE

Jack Sellers, P.E., Ed.D.

Learning lessons from family history

As a result of my careers as an electrical engineer, a flight instructor and a college professor, I have come to appreciate the value of learning from the past. I have learned some of the most critical lessons about health from my own family. Since my mother died of colon cancer and my father from lung cancer, I have been very aware of my own cancer ri

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Research & Treatment

Outfoxing an elusive quarry

Prostate cancer is a man’s cancer, so it is not surprising that most prostate tumors depend on something “manly” — testosterone and other male hormones — to grow.

The fountain of cellular youth

It is one of the great wonders of life: Stem cells have the remarkable ability to remain forever young until coaxed to develop into their adult roles as nerve, muscle, blood or other cells. Scientists call this seemingly magical flexibility “stemness.”

Treatments post triple threat to esophageal cancer

Tell someone not to swallow, and it may as well be an instruction not to sleep, blink or breathe. For those facing esophageal cancer, though, trouble swallowing and eating is just the beginning.

Cells that lurk and linger beneath

In cancer, not all cells are created equal. Research is showing that some cancer cells — dubbed cancer stem cells — may play a key part in tumors’ growth, spread and recurrence.

GIFT PLANNING

Honoring the memory of a beloved mother

Melvin Ross was devoted to his late mother, Lillian, who died of cancer. In her honor, Ross bequeathed his entire estate of about $5 million to City of Hope to aid research into the disease. Tragically, cancer claimed his own life in 2005.

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Recent Grants

NCI award supports research regarding melanoma and sarcoma

The National Cancer Institute (NCI) awarded a five-year, $1.4 million grant to Richard Jove, Ph.D., director of City of Hope’s Beckman Research Institute and deputy director of the Comprehensive Cancer Center. Jove’s research will set the stage for testing a new generation of antitumor and antiangiogenesis therapeutics. The research aims to develop more effective molecular-targeted therapies for melanoma and sarcoma.

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H.N. & Frances C. Berger Foundation continues graduate school support

Four high-achieving, first-year graduate students at City of Hope’s Graduate School of Biological Sciences received H.N. & Frances C. Berger Fellowship awards. The H.N. & Frances C. Berger Fellowships for Outstanding Performance will support the students’ first-year expenses as they pursue careers in biomedical research. The H.N. & Frances C. Berger Foundation has supported City of Hope’s graduate program since 2002.

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