A Quarterly Publication of City of Hope | Volume 21 Number 1 | Summer 2010

Molecular epidemiologist named first Morris & Horowitz Families Professor

By Shawn Le
Photo by p.cunningham

Susan Neuhausen

Prominent molecular epidemiologist Susan L. Neuhausen, Ph.D., has joined City of Hope as professor of population sciences and is the first Morris & Horowitz Families Professor in Cancer Etiology and Outcomes Research.

Neuhausen investigates the genetic causes of diseases and their connections to the environment so that researchers may identify ways to lower disease risk. Already a collaborator with other City of Hope researchers, she will contribute extensive knowledge and experience to cancer genetics and outcomes research in the Department of Population Sciences.

She joined City of Hope from the University of California, Irvine (UCI), where she served as associate director of the university’s Genetic Epidemiology Research Institute and professor in the departments of epidemiology and pediatrics. At UCI, she primarily performed research on breast cancer, prostate cancer and celiac disease.

“I’m honored to be named the first Morris and Horowitz Families Professor,” Neuhausen said. “It is one of many factors that contributed to my decision to join City of Hope. I’m especially excited for the potential to do long-term follow-up of patients to better understand and improve their disease-free survival.”

Neuhausen has several research project grants from the National Institutes of Health. One of her grants from the National Cancer Institute supports her investigation into the role that genes involved in insulin-like growth factor (IGF) signaling may play in the development of breast cancer. Findings from this study will provide information to more accurately assess breast cancer risk. Study findings also may suggest targets for therapy and help identify women who could particularly benefit from these new, IGF-targeting drugs.

She is interested in examining the entire continuum of cancer, from its origins to its outcomes.

“Molecular epidemiology is intrinsically linked to all the different divisions and fields of population sciences research,” Neuhausen said. “You can’t look at cancer without looking at all the components that contribute to it, such as genetics, environment, treatment outcomes and survivorship.”

Neuhausen holds a patent for her discovery of a specific chromosome mutation linked to prostate cancer risk. She has written chapters for several books and published research into genetic mutations and cancer risk in leading journals including Nature Genetics, Cancer Research, American Journal of Human Genetics and The Lancet. Additionally, she serves as a reviewer for numerous journals and is a member of the American Association of Cancer Research and the American Society of Human Genetics.

The Morris & Horowitz Families Professor in Cancer Etiology and Outcomes Research was established through a donation from longtime City of Hope supporters Monique and Doug Morris. Doug Morris, chairman and chief executive officer of Universal Music Group, was honored with The Spirit of Life© Award by City of Hope’s Music and Entertainment Industry group in 2008. The Morrises have a long-standing family tie to City of Hope. 

The professorship also honors the deep-rooted involvement of the Horowitz family in City of Hope. Zach Horowitz, a longtime leader of the Music and Entertainment Industry group, is a colleague of Doug Morris. Zach Horowitz’s father, Ben Horowitz, was formerly executive director of City of Hope; Ben Horowitz’s wife, Beverly Horowitz, previously headed City of Hope’s St. Louis office. And the couple’s daughter, Jody Horowitz Marsh, is a current City of Hope board member. 

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